3 Beta-(4-ethyl-3-iodophenyl)nortropane-2 beta-carboxylic acid methyl ester as a high-affinity selective ligand for the serotonin transporter

J Med Chem. 1997 Nov 21;40(24):3861-4. doi: 10.1021/jm970492z.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antidepressive Agents / chemical synthesis*
  • Antidepressive Agents / metabolism*
  • Antidepressive Agents / pharmacology
  • Binding, Competitive
  • Carrier Proteins / metabolism*
  • Cocaine / analogs & derivatives*
  • Cocaine / chemical synthesis
  • Cocaine / metabolism
  • Cocaine / pharmacology
  • Kinetics
  • Ligands
  • Male
  • Membrane Glycoproteins / metabolism*
  • Membrane Transport Proteins*
  • Mice
  • Mice, Inbred Strains
  • Nerve Tissue Proteins*
  • Selective Serotonin Reuptake Inhibitors / chemical synthesis*
  • Selective Serotonin Reuptake Inhibitors / metabolism*
  • Selective Serotonin Reuptake Inhibitors / pharmacology
  • Serotonin Plasma Membrane Transport Proteins
  • Structure-Activity Relationship

Substances

  • 3-(4-ethyl-3-iodophenyl)nortropane-2-carboxylic acid methyl ester
  • Antidepressive Agents
  • Carrier Proteins
  • Ligands
  • Membrane Glycoproteins
  • Membrane Transport Proteins
  • Nerve Tissue Proteins
  • Serotonin Plasma Membrane Transport Proteins
  • Serotonin Uptake Inhibitors
  • Slc6a4 protein, mouse
  • Cocaine